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Dr. Candace Tingen
Dr. Candace Tingen has joined the Office of Research on Women’s Health at the NIH as a AAAS Science and Technology Policy Fellow. Candace earned her PhD from Northwestern University in the Woodruff lab studying ovarian development before puberty. She then served as the Director of Research Programs for the Institute for Women’s Health Research and coordinator for the Illinois Women’s Health Registry.
- Candace Tingen Introduction
- When did you know that you wanted to become a scientist?
- What is your favorite thing about your job?
- What are you looking forward to in your new role at the NIH?
- What is a primordial follicle?
- What is a nurse cell?
- How is DNA organized?
- What does a gene do?
- What is the relationship between DNA, genes, chromosomes, and base pairs?
- What are two ways in which scientists can look at differences in genes?
- What is PCR?
- How does PCR work?
- Why do I need to add a primer to my sample?
- What is an example of PCR used in research in the Woodruff Lab?
- Why did the mouse have glowing ovaries?
- What is electrophoresis?
- What is a DNA ladder?
- What makes one band move farther than another?
- What makes one band brighter than another?
Robin Skory is a graduate student in the MD/PhD program at Northwestern. She graduated from Boston College where she received a B.S. in Biochemistry. Before entering medical school, she worked with high risk breast and ovarian cancer patients at Dana Farber Cancer Institute and ultimately hopes to combine her clinical and research work to improve the lives of those facing and surviving cancer. She is currently interested in studying luteinization and improving in vitro ovarian follicle culture.
- Robin Skory Introduction
- What do you like to do outside of the lab?
- What is the best part of working in the lab?
- How did you decide to become a scientist?
- What is an ELISA?
- How does an ELISA work?
- How do I analyze the results of my ELISA?
- Why is an ELISA useful?
- What is a gene?
- How can we look at differences in human DNA?
- How is DNA similar among all humans?
- Is human DNA similar to other species?
- How was PCR developed?
- What are the steps of PCR?
- What does it mean to 'amplify' a DNA segment?
- What is a primer?
- What are applications of PCR in science?
- What if I make a mistake during my PCR?
- How does electrophoresis work?
- Why is a DNA ladder important?
- How do the bands move on a gel?
- How can I see the bands on the gel?
- Is each band a gene?
- What is DNA?
Dr. Teresa Woodruff
Teresa Woodruff is the Thomas J. Watkins Professor of Obstetrics and Gynecology at the Feinberg School of Medicine at Northwestern University. Dr. Woodruff is a reproductive endocrinologist who has focused her research career on female reproductive health and infertility. She is the Chief of the Division of Fertility Preservation at the Feinberg School of Medicine. As the director of the Oncofertility Consortium, Dr. Woodruff collaborates with a team of oncologists, fertility specialists, social scientist, educators, and policy makers in her work. Dr. Woodruff also serves as an advocate for gender inclusivity in basic science research and is the Founder and Director of the Institute for Women’s Health Research. She is an educator and mentor in her field, developing the Women’s Health Science Program at Northwestern.
- How did you know that you wanted to be a scientist?
- How did you become a research scientist?
- What does it mean to be a director of a lab?
- Teresa Woodruff Introduction
- Teachers - Intro to NUBIO
- What will students get out of doing NUBIO labs?
- What will we study in this curriculum?
- What is meant by the 'bench to bedside approach'?
- What are the fertility preservation options for a women facing cancer treatment?
- What are the fertility preservation options for a man facing cancer treatment?
- What does it mean when a procedure is 'experimental'?
- What is the NUBIO curriculum?
- What is oncofertility?
Kristin Smith is a Patient Navigator with the Oncofertility Consortium. Kristin studied at Indiana University. Kristin meets with patients and their families after a cancer diagnosis in order to discuss fertility preservation options. She then serves as a resource and liaison for the patients and the clinicians in helping to coordinate fertility preservation into the patients’ care and treatment.
- Kristin Smith Introduction
- What is a patient navigator?
- Do other hospitals have patient navigators?
- What lead you to this job?
- What do you enjoy about your job?
- What is the most challenging thing about your job?
- What are the effects of cancer treatment for women, related to reproductive health?
- What are the fertility preservation options for pre-pubertal girls?
- What are the fertility preservation options for post-pubertal women?
- With whom else does a patient navigator collaborate?
- What are some self-care strategies for healthcare providers?
- How does the patient navigator help patients weigh risks and benefits of different options?
- How do patients understand which options are still experimental?
- Are experimental procedures more risky?
- What are the rights and responsibilities of the parents of the patients?
- What is the difference between consent and assent?
- What would be your response to patient #1, Grace?
- What would be your response to patient #2, Boyd?
- How would you balance Boyd's wishes with that of his parents?
- Boyd has mixed emotions about talking to you. How would you approach this conversation?
- What are the effects of cancer treatment for men, related to reproductive health?
- What are the fertility preservation options for males?
- How can I offer support to someone who has cancer?
- Where can I go if I want more information about fertility preservation?
- Some of these symptoms describe how I feel. Could I have cancer?
- How does informed consent apply in oncofertility to both minors and adults?
Dr. Kai Orton
Dr. Kai Orton is a postdoctoral fellow in the Woodruff lab. She utilizes bioinformatics in her work, incorporating computer science and information technology into her approach to biology and medicine.
- Kai Orton Introduction
- What is bioinformatics?
- How did you choose science as a career choice?
- What do you like to do outside of work?
- Why is it important to use a scientific notebook?
- How is the notebook important in research?
- What do the different tabs mean?
- How can scientists get things wrong?
- Are there standard methods of keeping a notebook?
- Are students' notebooks different from those of a practicing scientist?
- What kinds of information should go in a scientific notebook?
Dr. Miranda Bernhardt
Dr. Miranda Bernhardt is currently a postdoctoral fellow at the National Institute of Environmental Health Sciences in North Carolina. Miranda was a graduate student in the Woodruff lab as she completed her PhD in the Integrated Life Sciences Program at Northwestern University in 2011. Her thesis work was focused on the role of metal ions during meiotic maturation in mouse oocytes. She graduated from the University of Minnesota in 2005 with a BS in Genetics, Cell Biology, and Development.
- What is alginate?
- Miranda Bernhardt Introduction
- Why are you interested in reproductive biology?
- What project do you work on in the Woodruff lab?
- How do you see the zinc spark?
- How did you decide to become a scientist?
- What do you like to do outside of work?
- Do scientists really use the scientific method?
- What are some other uses for alginate?
- How is alginate used in the Woodruff lab?
- Why is the concentration of alginate important?
- What methods of encapsulation are used in the Woodruff lab?
- What are some of the effects of having low testosterone?
- What are the effects of high testosterone?
- What is testosterone?
- What is a gonadotropin?
- What is a hormone receptor?
- What role does testosterone play in infant development?
- What role does testosterone play in puberty and adulthood?
- What is an androgen?
- What is a serial dilution?
- How to use a micropipet - part 1
- How to use a micropipet - part 2
- What role does testosterone play in fetal development?
Dr. Min Xu
Dr. Min Xu is a Research Associate Professor at Northwestern University. He joined the Woodruff lab as a postdoc in July 2004 where he works on invitro follicle culture. Min earned his MD and PhD from Nanjing Medical University in China.
- Min Xu Introduction
- What do you enjoy most about your job?
- When you were in high school, did you know you wanted to be a scientist?
- Outside of work, what do you like to do?
- What are the uses of alginate?
- Where do the research follicles come from?
- What is one posssible method of encapsulation?
- How is an ELISA used?
- What are the steps in an ELISA?
- What are some of the different hormones that can be measured using an ELISA?
- Why do I have the set of standards on my ELISA plate?
- How is ELISA used in oncofertility research?